AL WALLACE RODRICK ET (EN) — MATHEMATICAL APPROACH TO MULTILEVEL, MULTISCALE HEALTH INTERVENTIONS, A

Тут можно читать онлайн книгу AL WALLACE RODRICK ET (EN) - MATHEMATICAL APPROACH TO MULTILEVEL, MULTISCALE HEALTH INTERVENTIONS, A - бесплатно полную версию (целиком). Жанр книги: Иностранная литература. Вы можете прочесть полную версию (весь текст) онлайн без регистрации и смс на сайте Lib-King.Ru (Либ-Кинг) или прочитать краткое содержание, аннотацию (предисловие), описание и ознакомиться с отзывами (комментариями) о произведении.

MATHEMATICAL APPROACH TO MULTILEVEL, MULTISCALE HEALTH INTERVENTIONS, A
Язык книги: Английский
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MATHEMATICAL APPROACH TO MULTILEVEL, MULTISCALE HEALTH INTERVENTIONS, A краткое содержание

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This book, based on published studies, takes a unique perspective on the 30-year collapse of pharmaceutical industry productivity in the search for small molecule “magic bullet” interventions. The relentless escalation of inflation-adjusted cost per approved medicine in the United States — from $200 million in 1950 to $1.2 billion in 2010 — has driven industry giants to, at best, slavish imitation in drug design, and at worst, abandonment of research and embracing of widespread fraud in consumer marketing.The book adapts formalism across a number of disciplines to the strategy for design of mutilevel interventions, focusing first on molecular, cellular, and larger scale examples, and then extending the argument to the simplifications provided by the dominant role of social and cultural structures and processes in individual and population patterns of health and illness.In place of “magic bullets”, we must now apply “magic strategies” that act across both the scale and level of organization. This book provides an introductory roadmap to the new tools that will be needed for the design of such strategies.Contents:Beyond Magic BulletsExpanding the TheoryDynamic ‘Regression Models’An Evolutionary ExcursionExample: Mental DisordersExample: Protein FoldingExample: Glycome DeterminantsExample: Glycan/Lectin Logic GatesExample: IDP Logic GatesTreatmentHistory and HealthBeyond GlasperlenspielMathematical AppendixReadership: Undergraduate, graduate, researchers and professionals in biomathematics, biostatistics, mathematical modeling, complex systems and pharmaceuticals.

MATHEMATICAL APPROACH TO MULTILEVEL, MULTISCALE HEALTH INTERVENTIONS, A - читать онлайн бесплатно полную версию (весь текст целиком)

MATHEMATICAL APPROACH TO MULTILEVEL, MULTISCALE HEALTH INTERVENTIONS, A - читать книгу онлайн бесплатно, автор AL WALLACE RODRICK ET (EN)

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